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doi: 10.1091/mbc.e04-06-0522 42 RossFPChappelJAlvarezJISanderDButlerWTFarach-CarsonMCet al

The test identifies genetic predispositions in four critical areas: GLP-1 receptor sensitivity, glucose-dependent insulinotropic receptor (GIPR) function, melanocortin-4 receptor (MC4R) signaling, and fat mass and obesity-associated (FTO) gene variants

Leptin modulates the expression of catabolic genes in rat nucleus pulposus cells through the mitogen-activated protein kinase and janus kinase 2/Signal transducer and activator of transcription 3 pathways