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Tumors can control ROS levels through products produced by the glutamine metabolic pathway, and the most important pathway for glutamine to control ROS is glutathione synthesis [91]

Clinical interventional with placebo supplementation for three months did not produce any changes in these cytokines levels

Given the characteristics of short-lived free radical species, which are challenging to confirm as transferring between cells through gap junctions after APAP overdose, we employed a thioacetamide-induced hepatotoxicity model