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Description

In addition to amino acid residue substitutions, structural modifications that extend the half-life are incorporated

James Reichman, M.D

The proglucagon gene (gcg) encodes for glucagon as well as two glucagon-like peptides, GLP-1 and GLP-2 ( Figure 2 summarizes the tissue-specific post-translational processing of proglucagon by PC1/3 and PC2, the resulting peptide products, and their receptor targets