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Moreover, UOx gene knockout mice exhibited attenuated toxic effects of 6-OHDA, suggesting a neuroprotective effect of UA [103]

Conclusions In conclusion, we suggest that Dihexa rescues cognitive impairment and recovers memory by ameliorating neuronal loss and inhibiting inflammation and glial activation via PI3K/AKT signaling pathways in APP/PS1 mice

4A), the desensitization of D 3 R (Fig

Interplay Nrf2/NF-B and CBP Dissecting the fine regulation of Nrf2-mediated transcriptional activity and its interactive nexus at the nuclear level is an arduous task, especially considering the complicated nuclear network that includes epigenetic regulation