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One systematic review and network meta-analysis of thirteen studies, published in Springer, evaluated three administration routes of vitamin B12: oral, intramuscular, and sublingual routes

Some protocols recommend intramuscular injection into the worked muscle ("site injection"), with the theory that local IGF-1R stimulation drives localized hypertrophy

When administered, it stimulates insulin secretion in response to food intake, helping to regulate blood sugar levels

Professional treatments like IV drips or injections may show quicker results, but topical products generally take a bit longer and require patience