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The study identified 5-Amino-1MQ from a series of 1-methylquinolinium analogues through PAMPA and Caco-2 permeability screening and confirmed its high selectivity for NNMT over related SAM-dependent methyltransferases
1Pharmacokinetic and pharmacodynamic studies with CJC-1295, a long-acting growth hormone releasing peptidePubMed / Journal of Clinical Endocrinology & Metabolism 2006 2Ipamorelin, the first selective growth hormone secretagoguePubMed / European Journal of Endocrinology 2001
Eur J Pediatr 153:488491
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