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Results IF increases the abundance of crown-like structures in AT To study AT plasticity in response to fasting cues, we induced obesity in mice by feeding them a 60% high-fat diet (HFD) for 12 weeks before challenging them with a 4:3 cyclic IF regimen (consisting of 3 fasting days and 4 feeding days per week, 24 h each) for 18 days (Supplementary Fig

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Jia Y, Liu Y, Feng L, Sun S, Sun G (2022) Role of glucagon and its receptor in the pathogenesis of diabetes

Y1-R and Y2-R agonism to stimulate G i proteins and to inhibit adenylyl cyclase was monitored by detecting the ability of PYY peptides, GEP44, or GEP12 to counteract the ability of Adenosine (acting through endogenous A2B receptor and Gs proteins) to increase levels of cAMP