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Signs You May Have Toxic Overload Chronic toxic burden often presents as multi-system symptoms, including: Brain fog, memory issues, slowed thinking Migratory joint pain or unexplained muscle aches Chronic fatigue, burnout, post-exertional crashes Neuropathy, tingling, internal vibrations, twitching Sensitivity to light, sound, chemicals, or fragrances Digestive instability: bloating, constipation, diarrhea, nausea Sleep disturbances or unrefreshing sleep Anxiety, irritability, mood changes Hormonal instability or irregular cycles POTS-like symptoms, palpitations, dizziness Rashes, hives, eczema, psoriasis Weak immunity or frequent infections These symptom clusters are common in mold toxicity, Lyme disease, MCAS, chemical sensitivity, post-infectious syndromes, and complex chronic illness

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta