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However, ectopic expression of TRPM7 restores their shear sensitivity, leading to a marked reduction in intravasation and metastatic lesion formation [220]

The complex pathophysiology and the metabolic risk factors shared between type 2 diabetes, obesity, CKD and cardiovascular disease have led to the concept of a cardiovascularkidneymetabolic (CKM) syndrome

Biochimie 86 , 825831 (2004)

[DOI] [PubMed] [Google Scholar] [172].Moosmann B, Behl C, Selenoproteins, cholesterol-lowering drugs, and the consequences: revisiting of the mevalonate pathway