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Gristan Y, Patel P, Moosavi L
[127] [128] Synthesis [edit] Biosynthesis [edit] Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III
More directly, nitrogen load also directly impacts the equilibrium of nitrogen equivalents between astrocytic glutamine storage and other nitrogen-rich metabolites including L-arginine, which is a key substrate for synthesizing many nitrergic metabolites (Ligthart-Melis et al., 2008
The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences
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