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Given the upstream regulatory effects of LTF on A and Tau, it is tempting to speculate that LTF acts as a signaling molecule with differential effects dependent on iron loading status, that once there is free iron released into the system would increase the antimicrobial response by upregulating the response of other AMPs

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More specifically, stakeholders will have the opportunity to discuss similarities and differences in disease pathophysiology and drug response across age groups, the extent to which efficacy data can be extrapolated from adults to children, and more