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performed a study on primary culture of OFs obtained from GO patients and control subjects, demonstrating that superoxide radicals induced an increased proliferation of OFs from GO patients compared with control fibroblasts ( The hypothesis that oxidative stress contributes GO pathogenesis was also suggested by studies performed by Tsai et al

In contrast to epimastigote forms of T

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Leiter, who is also a professor of medicine and nutritional sciences at the University of Toronto