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Ghrelin, primarily known as an orexigenic hormone that increases appetite, also interacts with the HPT axis, generally suppressing TSH and influencing thyroid hormone levels, but the direction and magnitude of these effects depend on physiological context and species

Pharmacology 61 , 154166 (2000)

Quick references and evidence quality The conclusions above are grounded in pooled human randomized trials and multiple metaanalyses through 2024

perfoliata derived extracellular vesicles (EVs) (Wititkornkul et al ., Reference Wititkornkul, Hulme, Tomes, Allen, Davis, Davey, Cookson, Phillips, Hegarty, Swain and Brophy2021)