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Similar content being viewed by others Background Oxidative stress (OS) is a toxic cellular status due to the imbalance between oxidant and antioxidant mechanisms resulting from increased production of oxidants, a dysfunction in the antioxidant system, or both [1, 2]

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While some Zur proteins bind DNA only in the presence of Zn II ions, 330,434,435 others showed ZurDNA binding in the presence of Zn II , Mn II , and Cd II , which again suggests that the cellular milieu enforces a metal specificity profile (Figure 8) that cannot be recapitulated by simple In vitro experiments