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Numbness and weakness occurring together most often point to a nerve problem either in the peripheral nervous system (such as peripheral neuropathy, a herniated disc, or carpal tunnel syndrome) or the central nervous system (such as stroke, MS, or spinal cord compression)

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Literature Search Strategy A comprehensive literature search was conducted on Medline, Embase, Emcare, The University of Melbourne full-text journals repository, Google Scholar and Evidence-Based Medicine (EBM) reviews (including the following databases

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