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Based on similar medications, retatrutide probably won't be recommended for: People with a personal or family history of medullary thyroid cancer Those with multiple endocrine neoplasia syndrome type 2 Anyone with a history of pancreatitis Pregnant or breastfeeding women Children and adolescents (under 18) People with severe kidney or liver disease Now, what about people without diabetes who want to lose weight

However, more robust, controlled, prospective studies with a longer follow-up are required in order to define the efficacy of these procedures in PWS patients

Severe abdominal pain: Especially if the pain is sudden, sharp, or cramping

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