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Similarly, impact of treatment on NAR was maximised by Al + SeNP-MT 2 over Al toxicity rescuing the biomass accumulation in leaves 14.70%

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Hagen TM., et al

So, for women who are following Hormone Replacement Therapy (HRT) by taking a pill, the decreased absorption of the drugs can actually cause a sudden (but unwanted) drop in estrogen causing mood swings and hot flashes to unexpectedly return