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vehicle-treated controls also had a better inflammatory and oxidative stress profile, with significantly higher levels of glutathione peroxidase and lower levels of malondialdehyde in the liver as well as significantly lower circulating levels of C-reactive protein, interleukin-6, and tumor necrosis factor-

Taken together, these studies underscore that UV radiation-driven activation of ncRNAs forms a multilayered cytoprotective system in melanocytes, orchestrating pigmentation, inflammation control, DNA repair, and survival signaling

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