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These drugs have shown efficacy beyond glycaemic regulation, including significant weight loss, cardiovascular protection, and possible advantages for renal function

Seek medical advice if you are unable to keep fluids down or notice a significant reduction in urine output

For employer-sponsored self-insured plans, you may also have the option to request an independent external review

In contrast, a multicenter retrospective cohort study, including a higher-risk population (23% with CKD) reported slower eGFR decline and lower risks of CKD progression and doubling of serum creatinine among SGLT2 inhibitor users compared with GLP-1 receptor agonist users