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Ibuprofen (e.g., Advil, Motrin, Midol, Nurofen, Dalsi, etc.) is one of the most used non-steroidal anti-inflammatory drugs (NSAIDs) globally and is considered an essential medicine by the World Health Organization ( Ibuprofen is frequently detected in water systems due to its widespread use and improper disposal ( Ibuprofen mechanism of action involves the reversible inhibition of cyclooxygenase enzymes (i.e., COX-1 and COX-2)

Fulcher KD, Welch JE, Klapper DG et al (1995) Identification of a unique -class glutathione S-transferase in mouse spermatogenic cells

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