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doi: 10.1016/j.neuroscience.2016.03.056 68 SotoMCaiWKonishiMKahnCR

Additionally, SGLT2i can lower HbA1c levels by 0.5-1.0% and support weight loss ( Studies have indicated that increased expression of the sodium-hydrogen exchanger isoform 1 (NHE-1) is linked to heart failure and may contribute to the development of hypertrophy and cardiac injury during ischemia and reperfusion ( Of note, long-term use of SGLT2i may lead to a reduction in glycosuric efficacy, without a corresponding decline in cardiovascular benefits

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Left unchecked, GLP-1 stigma deepens both health and career inequities