Aescin exhibits a range of therapeutic effects, including antioxidant, antidiabetic, anti-inflammatory, vasoprotective, antibacterial, antipyretic, analgesic, and antiaging properties 32,33
The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]
82,98 Glutathione, vitamin C, vitamin E, and other enzymes such as SOD and catalase are antioxidants that help neutralize ROS and prevent cellular damage
The data was gathered and analysed at an organ-by-organ level and compared to what it would look like for a healthy person aged 10, 20, 30 and 40