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Any patient with diabetes considering oral tirzepatide should consult their primary care provider or endocrinologist in addition to the prescribing provider

Tirzepatide that has been exposed to temperatures above 86F (30C), kept at room temperature for more than 21 days before use, frozen at any time, or kept past its expiration date should not be used regardless of appearance

Patients typically receive these medications through an injection site , usually in the abdomen, thigh, or upper arm

The clinical significance of elevations in amylase or lipase with ZEPBOUND is unknown in the absence of other signs and symptoms of pancreatitis