dementia glp-1 Receptor Agonists Tied to Decrease in T2DM-Related Risk GLP-1 and Alzheimer's Disease: Research

In one clinical trial, 5 mg per week tirzepatide was slightly more effective than 1 mg per week semaglutide in reducing body weight and glycated hemoglobin (HbA1c)

Together they suppress appetite and improve glycemic control more strongly than either arm alone but that combined pull on the gut is also the reason someone who starts at a maintenance dose typically feels wretched

Once food passes through the gastrointestinal tract (GI), taste receptors, along with mechanosensors and chemoreceptors within the GI tract, transmit information via afferent branches of the vagus nerve and hormonal signaling (e.g., GLP-1, GIP, PYY, insulin, among others) (46)

(Ill dive into what helped me become aware of them in a sec.) What I Did to Lose Weight This was definitely not a one-trick-pony lifestyle shift to get my health on track