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Catcalytic cycle of human glutathione reductase near 1 angstrom resolution

Zhuo M, Guan Y, Yang X, Hong L, Wang Y, Li Z, Chen R, Abbas HA, Chang L, Gong Y, Wu N, Zhong J, Chen W, Chen H, Dong Z, Zhu X, Li J, Wang Y, An T, Wu M, Wang Z, Wang J, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG , Lee JJ, Heymach JV, Wistuba II, Kalhor N, Yang L, Yi X, Futreal PA, Glisson BS, Xia X, Zhang J, Zhao J

doi: 10.1038/sj.mp.4001925 26 SoleimaniMFAyubiEKhosronezhadSHaslerGAmiriMRBeikpourFet al

Regulating the profibrogenic cytokine TGF-, which is found to be elevated in fibrotic Autoimmune diseases such as systemic sclerosis