Packer recently proposed an intriguing hypothesis that DPP-4 inhibitors potentiate some endogenous peptides, such as stromal cell-derived factor-1, in addition to activation of GLP-1, and that unfavorable effects of those peptides on CV parameters (e.g., inflammation, fibrosis, plaque growth, and sympathetic activation) could prevail against the CV protective effects of GLP-1, possibly leading to worsened CV complications and HF [36, 37]
Comparing GLP-1 Receptor Agonists with Other Diabetes Treatments When considering treatment options for type 2 diabetes, GLP-1 receptor agonists offer distinct advantages compared with other glucose-lowering therapies, though the optimal choice depends on individual patient characteristics, preferences, and clinical circumstances
Tracking your symptoms when starting a GLP-1 drug can help you understand how your body responds
29 Fruits, Vegetables & Herbs: Selected for broad nutrient coverage, including fermented ginger and gelatinized maca.*