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Its long-acting nature allows long-term monitoring of receptor activation effects on metabolism

Back Deacon, DF, Johnsen, AH, Holst, JJ (March 1995) 'Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo', Journal Clinical Endocrinology Metabolism , 80/3, 952-7

A comprehensive review of randomized controlled trials (RCTs) reveals that semaglutide significantly reduces body weight and the risk of cardiometabolic diseases like heart attack, stroke, and insulin resistance in adults with an overweight or obese body mass index (BMI)