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doi: 10.1111/exd.12324 87 EmberleyEDNiuYLeygueETomesLGietzRDMurphyLCet al

97 In a model of lipopolysaccharide (LPS)-induced inflammation, liraglutide inhibited the polarization of pro-inflammatory microglia and promoted the polarization of anti-inflammatory microglia, diminished inflammatory cytokine expression, and decreased NF-B pathway activation

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The degree of synovial fibrosis was evaluated by calculating the positive area of collagen fibers and the percentage of collagen I positive areas with ImageJ (National Institutes of Health, USA, available at TUNEL staining The degree of apoptosis was detected by TUNEL staining in synovial tissues