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If you have established cardiovascular disease and are overweight or obese, ask your doctor whether Wegovy's cardiovascular risk reduction indication applies to you

In clinical trials, average weight loss was approximately 1015% of body weight with semaglutide and 1522% with tirzepatide over 6872 weeks when combined with lifestyle changes

Vegetarians and vegans, since B12 is primarily found in animal-based foods, may experience a deficiency that can become significant over time

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