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The numerous health concerns associated with obesity, such as heart disease, diabetes, high blood pressure, and a shortened lifespan, can be reduced by losing weight and keeping it off

Because retatrutide is unlicensed, it may only be used lawfully in the UK within an authorised clinical trial (as an Investigational Medicinal Product, or IMP) or under specific MHRA-regulated frameworks for unlicensed medicines

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Wegovy significantly reduced the risk of major adverse cardiovascular events (cardiovascular death, heart attack, and stroke), which occurred in 6.5% of participants who received Wegovy compared to 8% of participants who received a placebo