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Caruntu D, Remond Y, Chou NH, Jun M-J, Caruntu G, He J, Goloverda G, O'Connor C, Kolesnichenko V (2002)

Appetite cues often change on GLP-1, and eating past fullness can feel uncomfortable

however, of those who showed glycemic control, there was a significantly lower incidence of hepatic encephalopathy.33 These two studies demonstrate that satisfactory glycemic control in cirrhotic patients can be achieved in only one third of cases by using current therapeutic schemes possibly because of hepatotoxicity, hypoglycemia and lactic acidosis, as most of antidiabetic drugs are metabolized in the liver.38 The recommendations of changes in diet and exercise regimens are empirical, as these measures have not been evaluated in patients with hepatic insufficiency

These drugs work by acting on different hormones that help regulate weight, insulin levels and craving centers in the brain