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The authors synthesized evidence that HGF/c-Met signaling is essential for brain development, synaptic plasticity, and cognitive function, with disruption of this pathway associated with cognitive decline in aging and neurodegenerative diseases

Taken together, our findings showed that the use of GLP-1RAs in type 2 diabetes patients with advanced DKD resulted in a neutral cardiovascular effect, better kidney function preservation, and lower mortality

Mechanisms : Effective in reducing adhesions and enhancing vascular health, it ensures an optimal environment for repair processes ( 6, 8, 10 )

This start-low,-go-slow approach balances efficacy with minimised GI side effects and improves adherence during the transition period