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doi: 10.1210/endocr/bqac118 99 BovoliniAGarciaJAndradeMADuarteJA

In patients receiving variable doses of GCs, intensive insulin therapy offers greater flexibility, as insulin dosing can be rapidly adjusted in response to changing steroid requirements

In the early 20th century it was noted to lower blood glucose concentrations in animals, but it was not until the 1950s that Jean Sterne studied dimethylbiguanide and subsequently developed Glucophage [2]

Especially, as trust in planning matters because planning is at the heart of increasingly contentious and at times polarising - debates about tackling global challenges around climate, access to housing, health, and inequality