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Subsequent examination indicated that (MeHg) 2 S is formed by the interaction of MeHg with reactive sulfur species (RSS), which exhibit high nucleophilicity 17,18 and include compounds such as GSH persulfide (GSSH) and protein-bound persulfide derived from CysSH persulfide (CysSSH) and hydrogen sulfide (H 2 S) produced by transsulfuration or enzymatic activities, such as cystathionine -lyase (CSE) activity 19 (see Fig

Apoptosis and expression of the Bcl-2 family of proteins and P53 in human pancreatic ductal adenocarcinoma