alzheimer's semaglutide UK Dementia Research Institute responds to news that Weight-loss drug semaglutide does not

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Our complete semaglutide vs tirzepatide comparison guide covers this in detail, but here are the key differences in weight loss outcomes: Average Weight Loss Comparison Semaglutide (STEP-1 trial, 68 weeks): Average weight loss: 14.9% 69.1% lost 10% or more 50.5% lost 15% or more Tirzepatide (SURMOUNT-1 trial, 72 weeks at 15 mg dose): Average weight loss: 22.5% 89% lost 10% or more 78% lost 15% or more Tirzepatide shows higher average weight loss in clinical trials, though both medications demonstrate significant effectiveness

While either drug can be quite effective, a recent study has found that people taking Zepbound (tirzepatide) have had better results than people taking Wegovy (semaglutide)

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