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51 These drugs primarily function by modulating neurotransmitter levels but cannot alter the course of the disease, 409,411 which are instructive for designing new drugs

Psychopathology in T21 differs from the abnormalities of other intellectual disability syndromes (Onnivello et al

Understanding this mutation allows functional medicine practitioners to recommend dietary supplementation with a specific form of folate, bypassing the compromised conversion process and reducing the risk of folate deficiency-related diseases

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