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Several factors can contribute to this more vulnerable environment: declining estrogen levels during menopause lower muscle mass during rapid weight loss reduced resistance training activity aggressive calorie restriction reduced protein intake lower mechanical loading through movement and exercise This does not mean GLP-1 medications directly cause osteoporosis

Mir Ali, a bariatric surgeon at Orange Coast Medical Center, explains: "Consuming a high amount of calories can still lead to weight gain or a plateau, even on these medications