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237 Similarly, KD enhanced the effectiveness of anti-CTLA-4 immunotherapy by reducing PD-L1 protein levels and augmenting the expression of interferons and antigen presentation-related genes

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Many experimental studies have shown that female mice are less susceptible to APAP hepatotoxicity than males and that the sex differences are substantial [17,18,35]

Chemotherapy and radiation therapy can cause the production of reactive oxygen species, which can damage DNA or interfere with DNA replication machinery through direct and indirect effects on malignant cells