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( Interesting and current review on the clinical physiology of GLP-1 and GLP-1 RA to understand their use in the treatment of obesity ) Nauck MA, Quast DR, Wefers J, Meier JJ

PMID: 52 GaynorJJCiancioGGuerraGSageshimaJHansonLRothDet al

In the LEADER trial, over 9,340 patients with type 2 diabetes and high cardiovascular disease risk underwent randomization to liraglutide or placebo and were followed for a median of 3.8 years resulting in a 13% risk reduction in a combined endpoint of death from cardiovascular cause, nonfatal myocardial infarction, or nonfatal stroke [46]

But definitive answers may only come with even longer follow-ups and more widespread usage