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On the other hand, analysis of a Hey1-eGFP transgenic reporter mouse line shows more prominent GFP signal in the peri-arterial, SOX17 + side of the villus capillary network and in large mesenteric arteries, reflecting the known role of Notch signaling in arterial specification (Fig

10.1016/j.physbeh.2018.07.014 Physiol

Common dose-limiting side effects include severe nausea, constipation, dehydration, and loss of appetite that becomes problematic rather than therapeutic

An ophthalmology expert could certainly talk about the eye conditions and permanent vision loss but may not be able to discuss intestinal obstructions or stomach paralysis