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Please see also the XGBoost documentation for additional information on model parameters ( SHapley additive exPlanations (SHAP) analysis We interpreted our ML models and assigned relative importance to variables influencing circulating TMAO levels by co-opting SHAP values, as expanded for tree-based ML models 28 and recently used to objectively evaluate factors driving metabolite plasma levels in humans 23

Mounjaro (tirzepatide) and Ozempic (semaglutide) are prescription medications that require evaluation and supervision by a licensed healthcare provider

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