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10.1016/j.lfs.2021.120111 465 UzunluluM.Telci CakliliO.OguzA

Oral glutamine supplementation increases seizure severity in a rodent model of mesial temporal lobe epilepsy

The relatively high systemic insulin levels counteract the lipolytic effects of the high GH levels in fat and muscle, but they do not reach adequate levels in the portal vein, so the liver remains under the control of GH, which still induces gluconeogenesis, increasing hyperglycemia [33]