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Endometriosis and medical therapy: from progestogens to progesterone resistance to GnRH antagonists: a review

Trends Endocrinol Metab (2011) 22(11):45866.10.1016/j.tem.2011.07.002 162 KumarDPRajagopalSMahavadiSMirshahiFGriderJRMurthyKSet alActivation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic beta cells

Add-On to Metformin A total of 546 adult patients with type 2 diabetes mellitus with inadequate glycemic control (HbA1c 7% and 10%) participated in a 24-week, placebo-controlled trial to evaluate FARXIGA in combination with metformin (NCT00528879)

Unlike earlier GH-releasing peptides, this combination stimulates physiological GH pulsatility while minimizing off-target endocrine effects