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[It] also aids in DNA synthesis and is involved in the metabolism of carbohydrates, fats, and proteins." Because it's so important, those with this type of vitamin deficiency, which is diagnosed via a blood test, are usually recommended to take either supplements or get regular B12 shots

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GSH can also serve as a substrate for S-glutathionylation of proteins in the presence of small redox enzyme glutaredoxins (GRX), which also utilizes GSH as a cofactor ( Figure 1 )