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In contrast, decreasing trends were observed in high-density lipoprotein (HDL)-related variables, the ratio of polyunsaturated fatty acids to total fatty acids, the ratio of polyunsaturated fatty acids to monounsaturated fatty acids, the ratio of omega-6 fatty acids to total fatty acids, and the ratio of linoleic acid to total fatty acids (Figures S2 and S3)

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Current evidence supports their use in patients with obesity or overweight status combined with weight-related conditions, though prescribing varies by healthcare setting and individual patient factors

GLP-1 agonists are useful drugs for the treatment of diabetes