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however, it also resulted in an undesired elevation in the controlled attenuation parameter (evaluating LFC)

When combined with insulin or other medications that affect blood glucose, hypoglycemia risk may increase if dose adjustments are not made by the prescribing physician

Whether the positive impact of GLP-1RAs on hepatic histology is indirect, i.e., through their action on extrahepatic tissues, or whether their action is direct, i.e., through activating GLP-1R on the hepatocytes, is still a controversial issue

This dual action makes semaglutide an effective agent in diabetes management, helping to maintain stable blood sugar levels and reduce HbA1c, a marker of long-term glucose control