Sano T, Coit DG, Kim HH, Roviello F, Kassab P, Wittekind C, et al
Potential Side Effects and Considerations While CJC-1295 is generally well-tolerated, there are some potential side effects to be aware of: Injection Site Reactions : Some individuals may experience redness, swelling, or irritation at the injection site
Cell Mol Life Sci 77(6):11151133 Zhang ZZ, Lee EE, Sudderth J et al (2016a) Glutathione depletion, pentose phosphate pathway activation, and hemolysis in erythrocytes protecting cancer cells from vitamin C-induced oxidative stress
The clinical escalation protocol from the Phase 2 NEJM trial established a specific titration schedule that increases the dose every four weeks, starting low and building to a target maintenance dose