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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Holman R.R., Bethel M.A., Mentz R.J., Thompson V.P., Lokhnygina Y., Buse J.B., Chan J.C., Choi J., Gustavson S.M., Iqbal N., et al

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2.2 Regulation of glutathione metabolism Glutathione is synthesized in the cytosol of all animal cells by the regulated action of gamma-glutamate cysteine ligase (-GCL), glutathione synthetase, glutathione reductase (GSR), and gamma-glutamyl transpeptidase (-GGT) and from which it is distributed to the other cellular compartments [8]