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Weight loss itself triggers changes in hormone levels, including shifts in estrogen, insulin, and leptin

However, it should be noted that the response of GPX4 inhibitors in different cancer cell lines is not consistent (Zou et al., 2019)

Phillip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine in Miami, Florida, and the George Washington University School of Medicine and Health Science in Washington, District of Columbia