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Most adverse events were gastrointestinal, such as nausea, diarrhea, or constipation, and occurred in 79.6% of the combination arm versus 39.9% of placebo recipients

We provide rubber boots (we do not have size 44 and up)

Acknowledgements The authors sincerely thank to Central Library and Departmental Library (Department of Zoology) of Baba Ghulam Shah Badshah University Rajouri, for providing access to different Journals and books for writing this article